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Wham clusters many of the candidate breakpoints and rounds their positions to the nearest tenth foundation pair. The placement with the highest browse help is described. If your comfortable-clipped consensus sequence might be aligned to the putative breakpoint location using the Smith-Waterman algorithm, the breakpoint is further refined to the loc
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The comfortable-clipped sequences that overhang the breakpoint are collapsed right into a consensus sequence using a various sequence alignment (MSA) delivered within the seqAn library [27]. Wham applies 3 filters on the consensus sequences. Breakpoints are not documented in conditions where by consensus sequences are shorter than ten bp or compris
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